While cg09249800 was the most statistically significant association, its effect size (−2.8 × 10−3) was nearly 4 times smaller than strongest effect size CpG which was cg26865747, (coefficient = 0.0105), proximal to the SCAND3 gene, a zinc finger transcription factor implicated in tumor proliferation and invasion44. The gene discussed is SCAND3; the disease is neoplasm.