We found that knockdown of PANX1 alone slightly decreased the number of tumor-infiltrating CD8+CD3+CD45+ T cells and effector/memory CD8+ T cells (Fig. 4C and Fig. S4B), and CD11c+MHC-IIHiCD11b+F4/80-CD3-CD45+ dendritic cells (Fig. 4D). The gene discussed is HLA-C; the disease is neoplasm.