INS and polycystic ovary syndrome: Our experiments show that trehalose can improve the body weight, polycystic ovary, and follicle number at all levels (by decreasing the number of atretic follicles, and increasing the number of primordial follicles, secondary follicles, and mature follicles), glucose tolerance Insulin resistance and T, E2, INS, and AMH hormone levels in PCOS mice.