PIGC and open-angle glaucoma: Of all the e/sQTL gene-tissue pairs that overlapped this locus targeting 24 genes, we identified an sQTL acting on PIGC, phosphatidylinositol glycan anchor biosynthesis class C, that significantly colocalized with the POAG cross-ancestry locus (spleen CLPP = 0.12, and arterial tissues RCP = 0.26-0.34; Supplementary Data 13 and Supplementary Fig. 13).