This includes the strongest normal tension glaucoma (NTG) association (9p21)8,46 in the POAG cross-ancestry (rs944801 OR = 1.26) and POAG EUR (rs6475604 OR = 1.3) GWAS meta-analyses that colocalized with a CDKN2A eQTL in brain cortex, CDKN2B-AS1 and RP11-149I2.4 sQTLs in pituitary, and CDKN2B eQTL in skeletal muscle (Supplementary Data 13). This evidence concerns the gene CDKN2A and open-angle glaucoma.