BCL3 regulation of STAT3 expression has been described in cervical [45], and glioblastoma cell lines [15], where shRNA knockdown of BCL3 resulted in decreased STAT3 and in the latter, pSTAT3 protein levels, while overexpression of BCL3 promoted the increase in STAT3 protein levels in both cell types. This evidence concerns the gene BCL3 and glioblastoma.