BCL3 and lymphoproliferative syndrome: The t(14;19) and BCL3-rearrangement (BCL3-R) have been identified in a broad spectrum of different tumor subtypes [62–66] and whilst BCL3 was originally identified in CLL, in a cytogenetic analysis of 4487 tumors diagnosed as lymphoproliferative disorder, the t14;19)q32;q13 was found in six cases [2], suggesting the translocation is quite rare.