BCL3 and glioma: Direct regulation of N-cadherin might suggest a role for BCL3 in epithelial to mesenchymal transition (EMT), and this is supported by demonstration of BCL3’s effects in mesenchymal differentiation and the regulation of EMT-related genes in A172 glioma cells [92], yet the weight of evidence in other tumour cell types suggests that while BCL3 may be regulated during EMT-MET flux, its influence is limited to the regulation of a subset of EMT and migration related genes and may not of itself induce EMT [108, 112].