Notably, the p200 family proteins, represented by IFI204, which is well known as an ALR and murine ortholog of IFI16 [46, 47], were markedly induced in bone marrow-derived dendritic cells (BMDCs) after infection by mouse hepatitis coronavirus (MHV), which belongs to the same genus betacoronavirus as SARS-CoV and MERS-CoV to mimic the acute RNA virus infection [48]. Here, IFI16 is linked to infection.