The results demonstrated that LCAT and DNASE1L3 were significantly downregulated in liver cancer cells, while NEIL3, GAGE4, SLC1A5, MMP1, SCIN and GAGE1 mRNA expression levels were notably elevated (Fig. 7A), in agreement with the bioinformatics prognostic model described above. The gene discussed is DNASE1L3; the disease is liver cancer.