In the current work, high β-catenin H score in IDC cases was significantly associated with advanced T stage, nodal metastasis, advanced AJCC stage, higher tumor grade, presence of necrosis, increased mitosis, poor NPI group, high grade of associated DCIS, ER negative, PR negative, Her2neu positive, high Ki67 proliferative index, Her2neu-enriched breast cancer, and non-luminal molecular subtype. This evidence concerns the gene MKI67 and breast cancer.