LYVE1 and infection: To further investigate the fate of these cells, we evaluated Lyve1 and MARCO expression in the dLN during infection with the attenuated CHIKV 181/25 strain, which does not disrupt dLN cellular organization (13), and its parental strain, the pathogenic WT CHIKV AF15561, at 8, 24, and 48 hours after infection using immunofluorescence confocal microscopy.