Mice with hepatocyte-specific depletion of torsinA (A-CKO mice) have markedly reduced secretion of TG-rich VLDL and severe steatosis, while livers from mice with hepatocyte-specific LAP1 deletion (L-CKO mice) demonstrate modest reductions in VLDL secretion and less severe steatosis (6). Here, TOR1AIP1 is linked to steatosis.