To investigate the potential role of LULL1 in hepatic steatosis and lipoprotein secretion, we crossed mice with 2 floxed alleles of Tor1aip2 encoding LULL1 (LUL-flox mice) with mice with an albumin-Cre transgene to obtain mice with depletion of LULL1 from hepatocytes (LUL-CKO mice) (Supplemental Figure 1 and Supplemental Table 1; supplemental material available online with this article; https://doi.org/10.1172/jci.insight.175328DS1). The gene discussed is TOR1AIP2; the disease is steatosis.