NDEL1 and lissencephaly spectrum disorders: Although NDEL1 variants have never been reported to cause lissencephaly in humans, previous studies have strongly linked NDEL1 to other lissencephaly genes such as LIS1 [17, 27, 81] and DYNC1H1 [32, 51], making NDEL1 a good candidate gene for lissencephaly.