The anti-human TROP-2 antibody AF650 and hIMB1636 were radiolabeled with 89Zr and 64Cu respectively for the detection of pancreatic cancer in tumor-bearing mice, and the tumors could be clearly visualized in PET images as expected (Chen et al. 2022; Li et al. 2022). This evidence concerns the gene TACSTD2 and familial pancreatic carcinoma.