The long non-coding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) and its target gene microRNA (miRNA)-34c were identified as regulators of inflammation and pyroptosis in diabetic kidney disease (DKD), mediated through the activation of the NLRP3 inflammasome [9] This suggests that the inhibition of NLRP3 inflammasomes may offer a therapeutic target for inflammation-related diseases. Here, NLRP3 is linked to diabetic kidney disease.