More complex macrophage phenotype analysis showed CD68+/pSTAT3+ inflammatory signaling macrophages were present both in the tumor and stroma, while CD68+/CD163+ immunosuppressive M2-like macrophages and CD68+/HLA-DR+ proinflammatory antigen-presenting macrophages more frequently populated the stroma (Figure 2D). This evidence concerns the gene CD163 and neoplasm.