A study in cell host and microbe found that HVEM expressed on type 3 innate lymphoid cells (ILC3) is crucial in suppressing pathogenic infections, where LIGHT acts as a ligand for HVEM, activating the HVEM signaling pathway to promote ILC3 secretion of IFN-γ to resist pathogenic infections (75). The gene discussed is TNFRSF14; the disease is infection.