IL6 and systemic inflammatory response syndrome: In comparison to the patients in cluster 2 with high thorax and low head injury, 58 patients in cluster 3 had high AIS for head (3.67 points) and thorax (3.17 points) injury and showed mainly a pro-inflammatory complication pattern (SIRS) accompanied with higher cytokine levels (IL-6 concentration of 229.61 pg/ml and IL-10 concentration of 56.52 pg/ml) and disease severity scores (APACHE II of 16.38 points and SOFA of 5.73) above average (Table 3).