The secretion of vesicles from leucocytes with immune modulatory properties, such as NK cytotoxicity, T cell activation and proliferation, and the ability of cells to produce IFN-γ, or delivering innate immune effectors (e.g., interleukins), are well-documented host responses to viral infections that these specific viruses could also hijack to evade the same responses [reviewed in (102)]. The gene discussed is IFNG; the disease is viral infectious disease.