To assure the clinical importance of HOXC6 in CRC, we assessed the relevance between the levels of HOXC6 (high/low) and the clinicopathological features of CRC patients from Zhongshan Hospital (n = 200, low HOXC6 n = 126; high HOXC6 n = 74). This evidence concerns the gene HOXC6 and colorectal carcinoma.