SCFAs do not act as a neuroactive substances class, but they play a pivotal role in preserving neurotransmitters (Coretti et al., 2018), inducing modifications in gene expression related to neurotransmitter systems, neuronal cell adhesion molecules, FA and lipid metabolism, inflammation, and mitochondrial function oxidative stress, all having possible relevance in autism (Nankova et al., 2014). Here, NRCAM is linked to autism.