The abundances of some effector T cells (CD4+ effector T cells, CD8+ effector memory T cells, etc.)were also increased in TB patients, as was also reported previously.[12] Most importantly, we found that the TB group had a higher ratio of immunosuppressive (CD4+ regulatory T cells) and non‐immunosuppressive T cells (other T cell subtypes) than the HC group (Figure 2d), although the difference did not reach significance. This evidence concerns the gene CD4 and tuberculosis.