Both VEGFA and ITGA9 have been found to be closely related to cell proliferation in the tumor environment.[24] It could be inferred that the potential relationship between the altered myeloid dendritic cell‐CD4+ regulatory T cell communication by the VEGFA‐ITGA9 pair and the imbalance of immunosuppressive and non‐immunosuppressive cells. The gene discussed is VEGFA; the disease is neoplasm.