RAB10 and Parkinson disease: Thus, and similar to what we previously reported for a different cohort of idiopathic PD LCLs52, LRRK2 kinase activity-mediated centrosomal cohesion deficits are detectable in a subset of idiopathic PD samples, even though they do not correlate with increased LRRK2 or pT73-Rab10 levels as assessed by quantitative Western blotting techniques.