BRD4 and triple-negative breast carcinoma: In contrast, BRD4 is overexpressed in various cancers including triple-negative breast cancer where it promotes oncogenesis (Stathis and Bertoni, 2018; Donati et al, 2018) largely, though not exclusively through MYC family members (Delmore et al, 2011; Slavish et al, 2020; Lenhart et al, 2015).