He et al. revealed that IL1B-induced SLC7A11 overexpression up-regulated PD-L1 and CSF1 through the αKG/HIF1α axis, which promoted TAM and MDSC infiltration, which providing a therapy direction for the inhibition of SLC7A11-mediated HCC metastasis [23]. Here, CD274 is linked to hepatocellular carcinoma.