Due to limited tumour tissue in the ID8-p53−/−Brca2−/− model, we did not perform further characterization of the myeloid compartment, but interestingly there were increased Ly6C+ cells (Fig. S8E), including inflammatory monocytes (F480+ MHC-II−) (Fig. S8F) and macrophages (F480+ MHC-II+) (Fig. S8G) in B16F10 tumours in Fgl2−/− mice, again suggesting that the absence of FGL2 promotes a TME primed for pro-inflammatory tumour targeting and elimination. This evidence concerns the gene TP53 and neoplasm.