CASP8 and infection: As expected, infection with ΔM36 MCMV or ΔM36, M45mutRHIM MCMV (lanes 3, 4, 8, and 9) stimulated more robust cleavage of caspase-8 and -3 than WT or M45mutRHIM MCMV (lanes 2, 5, 7, and 10).