CCND1 and cervical squamous intraepithelial neoplasia: In addition to its well-documented function as the regulatory subunit of an RB kinase, cyclin D1 conducts important non-canonical activities, including the induction of cell migration [23], coordination of gene transcription [12, 14], the induction of chromosomal instability (CIN), and the induction of DNA damage repair (DDR) [24–26].