EGF and congenital rubella syndrome: Meanwhile, a small set of molecules, such as Angiopoietin-1 (Ang-1), PDGF-AA, PDGF-AB/BB and EGF, were noticeable to be down-regulated as CRS progressed (Fig. 2a) and inversely associated with the severity of coagulation dysfunction (Supplementary Fig. 2b).