CCR7 and congenital rubella syndrome: Based on the two typical T cell immunophenotying markers CCR7 and CD45RA12, cytotoxic CAR-T in CRS was enriched for effector memory (CCR7- CD45RA−) and effector memory T cells re-expressing CD45RA (CCR7- CD45RA+), particularly accumulated at day 10~12 (Fig. 1e).