Based on the ClinVar database, GBA1 p.D179H was not previously reported to be associated with PD and identified in 4 cases, and eight controls in UK Biobank, 12 cases and 0 controls in 23andMe (OR = 3.4, 95%CI: 2.2–5.2, p = 4.3E-06). Here, GBA1 is linked to Parkinson disease.