GBA1 p.V433L (rs80356769, meta-analysis: P = 1.6E-04, OR = 4.2, 95% CI = 1.98–8.8) was present in ClinVar as a pathogenic PD variant, but also the previously linked autosomal dominant LRRK2 variant p.I2020T (rs35870237, P = 0.0004, OR = 21.4, 95% CI = 3.97–115.5) is considered pathogenic based on biological evidence36. Here, LRRK2 is linked to Parkinson disease.