SNCA and Parkinson disease: 43/336 variants passed a significance threshold of p < 0.05 (not Bonferroni), 3 of which have previously been linked to PD, and are located in dominantly inherited genes that our models could generate reliable statistical outputs for: LRRK2 p.N238I (rs28365216, OR = 9.4, 95%CI:1.5–58.1), GBA1 p.V433L (rs80356769, OR = 4.2, 95%CI: 2.0–8.8), and SNCA p.H50Q (rs201106962, OR = 2.0, 95%CI: 1.2–3.5).