We further investigated the anti-lymphoma activity of 7 × 19 CAR T cells in vivo by a single dose (5.0 × 106) of intravenous (I.V.)injection of anti-CD19 CAR T, 7 × 19 CAR T or control T cells into Nalm6 xenograft NOD/SCID mice. The gene discussed is CD19; the disease is lymphoma.