Since previous studies have found alterations with LINGO3 [44–47], BLCAP;NNAT [48–51] and SLC2A14 [52, 53] genes or associated functions in SZ and BD, it might be possible that an altered response to PA at the DNAm and/or gene expression levels may disrupt brain development and function in PT. This evidence concerns the gene BLCAP and Behcet disease.