Compared with women with T2D (n = 315), men with T2D (n = 414) were characterized by greater bone-free mass, total lean mass, trunk lean mass, limb lean mass and ASMI as well as lower total fat mass, total fat/lean ratio, trunk fat mass, trunk fat/lean ratio, limb fat mass, limb fat/lean ratio, fasting glucagon, and AUCglucagon. The gene discussed is GCG; the disease is type 2 diabetes mellitus.