CPSF3 and pancreatic adenocarcinoma: Consistent with this finding, CPSF3 expression was also significantly higher in the pancreatic adenocarcinoma (PAAD) data set from The Cancer Genome Atlas (TCGA) (n = 147) as compared to normal pancreata (n = 165) from the Genotype-Tissue Expression (GTEx) project (Fig. 1B).