CXCR4 upregulation in varying tumour entities render it as an attractive target to identify cancerous tissue5, which can be exploited using CXCR4-directed radiotracers, including the cyclic68Ga-labelled CXCR4-binding pentapeptide CPCR4.2 ([68Ga]Ga-PentixaFor)6. The gene discussed is CXCR4; the disease is neoplasm.