Per biological function analysis, the serine-threonine protein kinase Akt1, IL-6, the MAPK signaling, Vascular Endothelial Growth Factor (VEGF) and also tumor protein p53, were identified as resveratrol’s central targets in HCT-116 cells representing the most investigated CRC cell line [74]. The gene discussed is AKT1; the disease is colorectal carcinoma.