TP53 and colorectal carcinoma: In this context, this review describes a novel link between anti-functional plasticity (EMT, CSCs, metabolism), pro-apoptosis and modulation of p53 signaling pathway in CRC cell oncogenesis as one of resveratrol’s key mechanisms to suppress or reverse malignant phenotype, cell migration ability and resistance to conventional drugs in vitro and in vivo, suggesting a major therapeutic significance.