The phytopharmaceutical resveratrol is known as a potent anti-inflammatory agent, especially in CRC cells, where it modulates multiple inflows, activation mechanisms and consequences of inflammation’s main switch, particularly the transcription factor NF-κB, which represents one of the major pro-inflammatory transcription factors and regulates over 500 different genes [70]. The gene discussed is NFKB1; the disease is colorectal carcinoma.