Recently, donor-derived, EBV-specific CD8+T cells with high affinity WT1 specific TCR (TCRC4) generated persistent T cell responses in 12 patients with high risk AML post allogeneic hematopoietic cell transplantation (HCT), with higher relapse-free survival than HCT alone [43]. Here, WT1 is linked to acute myeloid leukemia.