The pathogenic variant c.920_923dup p.(His308Glnfs*16) was the most frequently encountered variant in USH2A-associated Usher syndrome (n = 5/5; families/patients), while c.397dup p.(His133Profs*7) was the most frequent variant for MYO7A-associated cases (n = 4/7; families/patients). This evidence concerns the gene USH2A and Usher syndrome.