Notably, levels of PD-L1 expression were positively correlated to Gleason score and its high expression is also associated with worse BCR-free survival, indicating that PD-L1 may be a co-factor associated with the progression of PCa, which is consistent with Juan He et al. and Gevensleben H et al.’s report [40, 41]. This evidence concerns the gene BCR and posterior cortical atrophy.