Survival analysis conducted using data from the TIMER2.0 website suggested that ccRCC patients exhibiting low TMEM25 expression, along with reduced infiltration of activated and resting mast cells, as well as resting NK cells, and elevated infiltration of Tregs, were associated with poorer clinical outcomes (Figure 5B–5G). The gene discussed is TMEM25; the disease is nonpapillary renal cell carcinoma.