TLR2 and peripheral arterial disease: There is an increasing body of literature documenting the heterogeneity of NET formation pathways (suicidal and non-lytic NET release, PAD-dependent and -independent, TLR2/1-dependent and independent),14,15,66 and in the future, our NET-array system can facilitate research to unravel the mechanistic links between NET size, formation pathways, and the modulation of NET release, potentially guiding therapeutic interventions in inflammatory diseases.