Recently, researchers used multiple AAV vectors to deliver DNA fragments through split introns, enabling trans-splicing of DNA fragments and achieving full-length ATP binding cassette subfamily A member 4 (ABCA4) gene (6.8 kb) in human retinal organoids and retinal cells of animal model, thus providing a kind of treatment strategy for Stargardt’s disease, the most common hereditary macular dystrophy in adolescents [148]. This evidence concerns the gene ABCA4 and Stargardt disease.