TNFRSF8 and classic Hodgkin lymphoma: A phase I study showed that the ORR of CD30 CAR-T therapy for R/R cHL patients was 33% (96), and a follow-up study showed that CD30 CAR-T therapy in combination with chemotherapy further improved the clinical outcome of patients with R/R cHL, with an ORR of 62% and 1-year PFS and OS of 36% and 94%, respectively (97).