According to Lang and partners, dendritic nanoparticles (Nano-sar) loaded with saracatinib effectively inhibited the invasion and metastasis of head and neck squamous cell carcinoma (HNSCC) by inhibiting Src kinase activity, which is a non-receptor tyrosine kinase, that promotes the growth and metastasis of HNSCC tumors (Fig. 6). This evidence concerns the gene NTRK1 and head and neck squamous cell carcinoma.