HMOX1 and Sepsis: Notably, proteins like serine protease inhibitor (Serine protease inhibitor) and heme oxygenase-1 (Hmox1), previously explored in sepsis, were among the identified targets (Chen et al., 2018b; Li et al., 2018; Ryter, 2021; Shutong et al., 2022; Yang et al., 2020).