In contrast, recent research on the role of UNC13C in the prognosis of HCC has suggested that high cytoplasmic expression of the protein may be paradoxically associated with increased American Joint Committee on Cancer (AJCC) T-staging, alcohol consumption, and a lower overall survival prognosis in HCC patients, thereby indicating possible oncogenic function acquired by UNC13C [6]. Here, UNC13C is linked to hepatocellular carcinoma.