Interestingly, for several lncRNAs including UCA1, and Taurine Up-Regulated 1 (TUG1 ) — were identified to have an inverse correlation with respect to expression, i.e., while UCA1 was upregulated in CRC tissues, it was downregulated in the EVs with respect to control. This evidence concerns the gene TUG1 and colorectal carcinoma.