In another study, two serum EV lncRNAs TGF-β Induced lncRNA (TBILA) and ArfGAP with GTPase Domain, Ankyrin Repeat And PH Domain 1 (AGAP2-AS1) were detected to be increased in NSCLC patients compared to controls and individually had an AUC of 0.775 and 0.734 respectively.145 When these were combined with the commonly used serum tumor biomarker Cyfra21-1, the specific diagnostic accuracy for NSCLC patients enhanced considerably (AUC = 0.853). Here, AGAP2 is linked to non-small cell lung carcinoma.