On the contrary, WWS cells are characterized by ECM and membrane proteins such as THBS2, COL18A1, FBN2, and HLA-A, while LGMD cells are better characterized by cytosolic and nucleus proteins such as CUL7, RIF1, and KMT2A (Fig. 7c). The gene discussed is COL18A1; the disease is limb-girdle muscular dystrophy.