The 10 most upregulated genes were in CD4+ EM cells both in exCOPD and NSCLC samples: AC008677.2, AC245033.4, AL450998.1, RPS18P9, RPS3AP5, EEF1A1P5, RPL27AP, RPL41P5, AC008481.1, and S100A9. This evidence concerns the gene RPS3AP5 and non-small cell lung carcinoma.