KL and chronic kidney disease: Ulteriorly, we calculated the relative risk (RR) of these variables, and we found that patients with α-Klotho ≥516.9 pg/ml was 6.699 times more likely to develop CKD than patients with α-Klotho <516.9 pg/ml (RR 6.699, 95% CI 1.631–27.519, p=0.007).