To elucidate the possible association of FAMGs with OS in COAD, univariate Cox analysis was carried out, and survival-related FAMGs (ACADL, ACBD4, ACOX1, ALAD, CD36, CIDEA, CPT2, ELOVL3, ELOVL6, ACOT11, ENO2, ENO3, HADH, MORC2, SUCLG2) were identified (p < 0.05) (Suppl. Here, ENO2 is linked to colon adenocarcinoma.