For example, HIPK2 could promote the epithelial‐mesenchymal transition (EMT) process of renal tubular epithelial cells and renal fibrosis through activating the Smad pathway, Notch pathway, NF‐kB pathway and Wnt/β‐catenin pathway.15, 16, 17. Here, NFKB1 is linked to renal fibrosis.